▩ ID9606/2a-c: Dispositive eines Virus
Cardiovascular Manifestations of Hepatitis C Virus


Type: Journal Article

Identifier:
4KKFSFFR
| issn:
1557-8224 Search publication in worldcat.org
| doi:
10.1016/j.cld.2017.03.003 Search article via doi.org
Description

Hepatitis C virus (HCV) infection is a prevalent condition associated with numerous extrahepatic manifestations. Epidemiologic studies have found that HCV is associated with increased cardiovascular morbidity and mortality, in particular with carotid atherosclerosis, cerebrovascular events, and coronary heart disease. The mechanisms involved encompass a chronic systemic inflammatory state, insulin resistance, and a potential, direct infection of the vascular endothelium. Sustained virologic response with interferon-based regimens is associated with reduced cardiovascular events, although this must be validated with newer direct-acting antivirals. This clear association between HCV and cardiovascular events may have significant economical and public health implications.


Related people

Goossens, Nicolas (creator)
Negro, Francesco (creator)